Nationwide project will track uterine fibroid treatment outcomes

A cohort of 10 clinical centers across the U.S. recently announced that they will collaborate on a large-scale study on the effectiveness of various treatments for uterine fibroids.

Uterine fibroids are a common type of benign tumor in women. Some are entirely asymptomatic, while others can cause significant pain, bleeding and fertility problems.

“Uterine fibroids affect a significant population of women across the country who require some form of treatment, including medication or surgery,” Erica Marsh, chief of the division of reproductive endocrinology and infertility at the U-M Department of Obstetrics and Gynecology and the principal investigator for the Michigan site, said.

The project will develop and populate a national registry that follows patients being treated for uterine fibroids and their outcomes over five years.

“Unfortunately, we don’t have data that allow us to compare outcomes between patients who receive different therapies for fibroids,” Marsh said. “Understanding how quality of life, recurrence rates and fertility rates differ between treatments is critical information for women, their families and clinicians who are making decisions about fibroid care. This effort will allow us to better counsel women on the outcomes they can expect from a given treatment.”

The study is being funded by The Patient-Centered Outcomes Research Institute, which is providing $20 million for the study.


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